Cystic Fibrosis Twin and Sib Study

Our work has been featured in prominent scientific journals, with a selection of those publications listed here:

• Genetic modifiers of nutritional status in cystic fibrosis (PDF)
• Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2 (PDF)
• A novel lung disease phenotype adjusted for mortality attrition for cystic fibrosis genetic modifier studies (PDF)
• Genetic modifiers play a substantial role in diabetes complicating cystic fibrosis (PDF)
• Interactions between Second Hand Smoke and Genes that Affect CF (PDF)
• Interaction between a novel TGFB1 haplotype and CFTR genotype is associated with improved lung function (PDF)
• Modifiers in CF Meconium Ileus (PDF)
• Problematic Variation In Local IRBs (PDF)
• Heritability of Lung Disease Severity In CF (PDF)
• Identification of IFRD1 Pulmonary Modifier (PDF)
• Susceptibility Gene for CFRD (PDF)
• Update on Gene Modifiers in CF (PDF)
• Modeling Framework to Evaluate Gene Modifiers (PDF)
• Location and Duration of Treatment in Respiratory Exacerbations (PDF)
• Quantification of the Relative Contribution of Environmental and Genetic Factors to Variation in Cystic Fibrosis Lung Function (PDF)
• Mutations That Permit Residual CFTR Function Delay Acquisition of Multiple Respiratory Pathogens in CF Patients (PDF)
• Modifier genes in Mendelian Disorders: the example of Cystic Fibrosis (PDF)
• Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2 (PDF)